- Білоусова, Наталя Анатоліївна (orcid.org/0000-0001-6732-426X), Несукай, Віталій Анатолійович (orcid.org/0009-0004-7394-3277), Сімагіна, Тетяна Володимирівна (orcid.org/0000-0001-5521-9331), Долженко, Марина Миколаївна (orcid.org/0000-0002-8559-9598), Шматенко, Олександр Петрович (orcid.org/0000-0002-6145-460Х), Соломенний, Андрій Миколайович (orcid.org/0000-0002-9562-8321) and Тарасенко, Вікторія Олександрівна (orcid.org/0000-0002-3614-6752) (2025) Adherence to treatment among patients with coronary heart disease with comorbid conditions: the impact of socio-economic factors during martial law in Ukraine (first message) Journal of Military Medicine, 1 (6). pp. 159-169. ISSN 2708-6615
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Abstract
Purpose. To assess the impact of socio-economic factors on treatment adherence among patients of coronary heart disease (CHD) with comorbid conditions in Ukraine during wartime. Materials and methods. The study was conducted at the Department of Cardiology of the P.L. Shupyk National University of Health Care of Ukraine. Patients with CHD with concomitant arterial hypertension, type 2 diabetes mellitus, and chronic kidney disease were surveyed using an online questionnaire via Google Forms between June and September 2024. Methods employed included systematization, generalization, deduction, induction, statistical analysis, and bibliographic review. Results. The study revealed that men demonstrated higher adherence to treatment compared to women (φ = 0.271, p=0.006). However, both genders equally tended to discontinue treatment when their condition either improved (φ = 0.468, p=0.000) or worsened (φ = 0.393, p=0.000). Patients of CHD with comorbid conditions facing one or two socio-economic risk factors exhibited the lowest adherence levels (76.2% [76.2 ± 0.04, p<0.0001]). Conclusions. Adherence to treatment among patients of CHD with comorbid conditions in Ukraine during martial law is influenced by gender, with men showing greater adherence. Nonetheless, both men and women frequently discontinue treatment upon experiencing changes in health status, either positive or negative. The study confirmed the significant impact of socio-economic risk factors on adherence. To address these challenges, the creation of multidisciplinary teams, including pharmacists, is recommended to reduce medication errors and improve adherence to pharmacotherapy in patients of CHD with comorbid conditions.
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